Androgen Deprivation Therapy Prevents Bladder Cancer Recurrence
Androgen deprivation therapy prevents bladder cancer recurrence. Although accumulating preclinical evidence indicates the involvement of androgen receptor signals in bladder cancer (BC) development, its clinical relevance remains unclear.
Androgen Deprivation Therapy Prevents Bladder Cancer …
14/12/2021 · AST was not associated with a lower risk of BCa incidence, but a subgroup analysis showed that patients receiving 5-ARIs had a reduced risk of BCa incidence. In addition, AST has a beneficial effect on the recurrence rates of bladder cancer. We did not observe any significant differences in AST on CSS, OS or PFS when compared with the control.
Impact Of Androgen Suppression Therapy On The Risk And …
22/03/2016 · Our recent retrospective study revealed a significantly reduced risk of bladder cancer (BC) recurrence in men who received androgen deprivation therapy (ADT) for their prostate cancer. However, whether androgen receptor (AR) signals contributed to the preventive effect of ADT remained unclear because ADT could reduce serum estrogens as well.
Expression Of Androgen Receptor In Non-muscle-invasive …
Androgen deprivation therapy for prostate cancer and the risk of bladder cancer: A systematic review of observational studies Urol Oncol. 2020 Nov;38(11):816-825. doi: 10.1016/j .urolonc ... our systematic review included 7 observational studies. Five studies reported a decreased risk of bladder cancer with ADT use, 1 study reported no association, and 1 study reported an …
Androgen Deprivation Therapy For Prostate Cancer And The …
01/11/2020 · Overall, our systematic review included 7 observational studies. Five studies reported a decreased risk of bladder cancer with ADT use, 1 study reported no association, and 1 study reported an increased risk. All studies had time-related biases, did not consider a lag period, and had potential residual confounding.
Androgen Deprivation Therapy For Prostate Cancer And The …
Introduction: Bladder cancer (BCa) is three-to-four times more common in men than in women. To explain this gender gap, several theories have been proposed, including the impact of androgen hormones. The aim of this study was to investigate the differential impact of androgen deprivation therapy (ADT) on subsequent risk of developing BCa in men with prostate …
The Effect Of Androgen Deprivation Treatment On …
Purpose: We determined whether intravesical recurrence is affected by inhibition of androgen signaling among men with nonmuscle invasive bladder cancer. Materials and methods: We examined the intravesical recurrence rate among men treated with or without androgen suppression therapy by androgen deprivation therapy for prostate cancer or 5α-reductase …
Suppressed Recurrent Bladder Cancer After Androgen …
AST was not associated with a lower risk of BCa incidence, but a subgroup analysis showed that patients receiving 5-ARIs had a reduced risk of BCa incidence. In addition, AST has a beneficial effect on the recurrence rates of bladder cancer. We did not observe any significant differences in AST on CSS, OS or PFS when compared with the control.
Frontiers | Impact Of Androgen Suppression Therapy On …
Purpose: This study aimed to investigate the effect of androgen suppression therapy (AST), comprising a 5-α reductase inhibitor (5-ARi) and androgen deprivation therapy (ADT), on the risk of bladder cancer incidence, recurrence, and mortality. Materials and methods: We used the PRISMA statement to report the methods and results of this meta-analysis. Bladder cancer …